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1.

Skin Î³Î´ T cell inflammatory responses are hardwired in the thymus by oxysterol sensing via GPR183 and calibrated by dietary cholesterol.

Frascoli, Michela; Ferraj, Enxhi; Miu, Bing; Malin, Justin; Spidale, Nicholas A; Cowan, Jennifer; Shissler, Susannah C; Brink, Robert; Xu, Ying; Cyster, Jason G; Bhandoola, Avinash; Kang, Joonsoo; Reboldi, Andrea.

Immunity; 56(3): 562-575.e6, 2023 03 14.

Artículo en Inglés | MEDLINE | ID: mdl-36842431

2.

Progress on thymic function from Maui.

Cowan, Jennifer; Bhandoola, Avinash.

Nat Immunol; 17(10): 1129-32, 2016 Sep 20.

Artículo en Inglés | MEDLINE | ID: mdl-27648536

3.

Trust your gut: an early life lesson for T cells.

Cowan, Jennifer E.

Trends Immunol; 42(10): 844-845, 2021 10.

Artículo en Inglés | MEDLINE | ID: mdl-34479799

4.

Diversity in Cortical Thymic Epithelial Cells Occurs through Loss of a Foxn1-Dependent Gene Signature Driven by Stage-Specific Thymocyte Cross-Talk.

White, Andrea J; Parnell, Sonia M; Handel, Adam; Maio, Stefano; Bacon, Andrea; Cosway, Emilie J; Lucas, Beth; James, Kieran D; Cowan, Jennifer E; Jenkinson, William E; Hollander, Georg A; Anderson, Graham.

J Immunol; 2022 Nov 14.

Artículo en Inglés | MEDLINE | ID: mdl-36427001

5.

Diversity in Cortical Thymic Epithelial Cells Occurs through Loss of a Foxn1-Dependent Gene Signature Driven by Stage-Specific Thymocyte Cross-Talk.

White, Andrea J; Parnell, Sonia M; Handel, Adam; Maio, Stefano; Bacon, Andrea; Cosway, Emilie J; Lucas, Beth; James, Kieran D; Cowan, Jennifer E; Jenkinson, William E; Hollander, Georg A; Anderson, Graham.

J Immunol; 2022 Nov 14.

Artículo en Inglés | MEDLINE | ID: mdl-36375838

6.

Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis.

Bosticardo, Marita; Yamazaki, Yasuhiro; Cowan, Jennifer; Giardino, Giuliana; Corsino, Cristina; Scalia, Giulia; Prencipe, Rosaria; Ruffner, Melanie; Hill, David A; Sakovich, Inga; Yemialyanava, Irma; Tam, Jonathan S; Padem, Nurcicek; Elder, Melissa E; Sleasman, John W; Perez, Elena; Niebur, Hana; Seroogy, Christine M; Sharapova, Svetlana; Gebbia, Jennifer; Kleiner, Gary Ira; Peake, Jane; Abbott, Jordan K; Gelfand, Erwin W; Crestani, Elena; Biggs, Catherine; Butte, Manish J; Hartog, Nicholas; Hayward, Anthony; Chen, Karin; Heimall, Jennifer; Seeborg, Filiz; Bartnikas, Lisa M; Cooper, Megan A; Pignata, Claudio; Bhandoola, Avinash; Notarangelo, Luigi D.

Am J Hum Genet; 105(3): 549-561, 2019 09 05.

Artículo en Inglés | MEDLINE | ID: mdl-31447097

7.

Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells.

Larsen, Brian M; Cowan, Jennifer E; Wang, Yueqiang; Tanaka, Yu; Zhao, Yongge; Voisin, Benjamin; Constantinides, Michael G; Nagao, Keisuke; Belkaid, Yasmine; Awasthi, Parirokh; Takahama, Yousuke; Bhandoola, Avinash.

J Immunol; 203(3): 686-695, 2019 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-31243087

8.

Aire controls the recirculation of murine Foxp3⁺ regulatory T-cells back to the thymus.

Cowan, Jennifer E; Baik, Song; McCarthy, Nicholas I; Parnell, Sonia M; White, Andrea J; Jenkinson, William E; Anderson, Graham.

Eur J Immunol; 48(5): 844-854, 2018 05.

Artículo en Inglés | MEDLINE | ID: mdl-29285761

9.

Osteoprotegerin-Mediated Homeostasis of Rank+ Thymic Epithelial Cells Does Not Limit Foxp3+ Regulatory T Cell Development.

McCarthy, Nicholas I; Cowan, Jennifer E; Nakamura, Kyoko; Bacon, Andrea; Baik, Song; White, Andrea J; Parnell, Sonia M; Jenkinson, Eric J; Jenkinson, William E; Anderson, Graham.

J Immunol; 195(6): 2675-82, 2015 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-26254339

10.

Thymus medulla fosters generation of natural Treg cells, invariant Î³Î´ T cells, and invariant NKT cells: what we learn from intrathymic migration.

Cowan, Jennifer E; Jenkinson, William E; Anderson, Graham.

Eur J Immunol; 45(3): 652-60, 2015 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-25615828

11.

Response to Comment on "Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells".

Larsen, Brian M; Cowan, Jennifer E; Bhandoola, Avinash.

J Immunol; 203(9): 2355-2356, 2019 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-31636133

12.

An essential role for medullary thymic epithelial cells during the intrathymic development of invariant NKT cells.

White, Andrea J; Jenkinson, William E; Cowan, Jennifer E; Parnell, Sonia M; Bacon, Andrea; Jones, Nick D; Jenkinson, Eric J; Anderson, Graham.

J Immunol; 192(6): 2659-66, 2014 Mar 15.

Artículo en Inglés | MEDLINE | ID: mdl-24510964

13.

Differential requirement for CCR4 and CCR7 during the development of innate and adaptive αßT cells in the adult thymus.

Cowan, Jennifer E; McCarthy, Nicholas I; Parnell, Sonia M; White, Andrea J; Bacon, Andrea; Serge, Arnauld; Irla, Magali; Lane, Peter J L; Jenkinson, Eric J; Jenkinson, William E; Anderson, Graham.

J Immunol; 193(3): 1204-12, 2014 Aug 01.

Artículo en Inglés | MEDLINE | ID: mdl-24990081

14.

Natural Th17 cells are critically regulated by functional medullary thymic microenvironments.

Jenkinson, William E; McCarthy, Nicholas I; Dutton, Emma E; Cowan, Jennifer E; Parnell, Sonia M; White, Andrea J; Anderson, Graham.

J Autoimmun; 63: 13-22, 2015 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-26143957

15.

Mechanisms of thymus medulla development and function.

Anderson, Graham; Baik, Song; Cowan, Jennifer E; Holland, Amanda M; McCarthy, Nicholas I; Nakamura, Kyoko; Parnell, Sonia M; White, Andrea J; Lane, Peter J L; Jenkinson, Eric J; Jenkinson, William E.

Curr Top Microbiol Immunol; 373: 19-47, 2014.

Artículo en Inglés | MEDLINE | ID: mdl-23612988

16.

Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla.

Desanti, Guillaume E; Cowan, Jennifer E; Baik, Song; Parnell, Sonia M; White, Andrea J; Penninger, Josef M; Lane, Peter J L; Jenkinson, Eric J; Jenkinson, William E; Anderson, Graham.

J Immunol; 189(12): 5519-26, 2012 Dec 15.

Artículo en Inglés | MEDLINE | ID: mdl-23152561

17.

Revelations in Thymic Epithelial Cell Biology and Heterogeneity from Single-Cell RNA Sequencing and Lineage Tracing Methodologies.

Morales-Sanchez, Abigail; Shissler, Susannah C; Cowan, Jennifer E; Bhandoola, Avinash.

Methods Mol Biol; 2580: 25-49, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-36374449

18.

Expression of the transcription factor Klf6 by thymic epithelial cells is required for thymus development.

Malin, Justin; Martinez-Ruiz, Gustavo Ulises; Zhao, Yongge; Shissler, Susannah C; Cowan, Jennifer E; Ding, Yi; Morales-Sanchez, Abigail; Ishikawa, Masaki; Lavaert, Marieke; Das, Arundhoti; Butcher, Donna; Warner, Andrew C; Kallarakal, Melissa; Chen, Jingqiu; Kedei, Noemi; Kelly, Michael; Brinster, Lauren R; Allman, David; Bhandoola, Avinash.

Sci Adv; 9(46): eadg8126, 2023 11 17.

Artículo en Inglés | MEDLINE | ID: mdl-37967174

19.

Process evaluation of an environmental and educational nutrition intervention in residential drug-treatment facilities.

Cowan, Jennifer A; Devine, Carol M.

Public Health Nutr; 15(7): 1159-67, 2012 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-22475412

20.

Postnatal Involution and Counter-Involution of the Thymus.

Cowan, Jennifer E; Takahama, Yousuke; Bhandoola, Avinash; Ohigashi, Izumi.

Front Immunol; 11: 897, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-32477366

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Skin Î³Î´ T cell inflammatory responses are hardwired in the thymus by oxysterol sensing via GPR183 and calibrated by dietary cholesterol.

Progress on thymic function from Maui.

Trust your gut: an early life lesson for T cells.

Diversity in Cortical Thymic Epithelial Cells Occurs through Loss of a Foxn1-Dependent Gene Signature Driven by Stage-Specific Thymocyte Cross-Talk.

Diversity in Cortical Thymic Epithelial Cells Occurs through Loss of a Foxn1-Dependent Gene Signature Driven by Stage-Specific Thymocyte Cross-Talk.

Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis.

Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells.

Aire controls the recirculation of murine Foxp3⁺ regulatory T-cells back to the thymus.

Osteoprotegerin-Mediated Homeostasis of Rank+ Thymic Epithelial Cells Does Not Limit Foxp3+ Regulatory T Cell Development.

Thymus medulla fosters generation of natural Treg cells, invariant Î³Î´ T cells, and invariant NKT cells: what we learn from intrathymic migration.

Response to Comment on "Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells".

An essential role for medullary thymic epithelial cells during the intrathymic development of invariant NKT cells.

Differential requirement for CCR4 and CCR7 during the development of innate and adaptive αßT cells in the adult thymus.

Natural Th17 cells are critically regulated by functional medullary thymic microenvironments.

Mechanisms of thymus medulla development and function.

Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla.

Revelations in Thymic Epithelial Cell Biology and Heterogeneity from Single-Cell RNA Sequencing and Lineage Tracing Methodologies.

Expression of the transcription factor Klf6 by thymic epithelial cells is required for thymus development.

Process evaluation of an environmental and educational nutrition intervention in residential drug-treatment facilities.

Postnatal Involution and Counter-Involution of the Thymus.